This paper presents the energy and exergy analyses of the different organic fluids which can be used in an organic Rankine cycle (ORC) adapted to a municipal solid waste power plant in the frame of energy recovery. It is known that, in a typical municipal solid waste power plant, a considerable amount of energy is sent up from a plant chimney to the atmosphere. This waste energy can be utilized by using an adapted ORC system with a proper organic fluid. Consequently, different organic fluids are examined and compared thermodynamically in this study. The optimal operation conditions of several organic fluids have been evaluated by means of ASPEN and EES software programs. The effects of the outlet temperature of heat source on the energetic and exergetic efficiencies, net power output, power consumption and mass flow rate at a given pinch point temperature difference (PPTD) have been investigated. It can be deduced from the analyses that, n-hexane has the highest energetic and exergetic efficiencies at all outlet temperatures of the heat source such as 8.92 % and 34.47 % at 82.08 °C, respectively. It can also be stated that the maximum net power output is obtained by using n-hexane.